ACTIVE
Lactobacillus Ferment Lysate
A ferment lysate made from lactic acid bacteria, used to help support skin's natural balance and barrier, and studied on skin for hydration.
Source
Fermented Lactobacillus bacteria, broken down (non-living)
Used for
Skin conditioning, comfortable-feeling skin
How it works
Lactobacillus Ferment Lysate is created by fermenting a Lactobacillus culture and then breaking down (lysing) the resulting cells, leaving behind a blend of ferment compounds, proteins and amino acids, not a live microorganism itself. It's used in skincare as a prebiotic-style ingredient that supports skin's own natural balance.
Studied on skin, a cosmetic made with ferment lysates of a lactic acid bacterium helped skin hold on to its moisture after its barrier had been challenged with a mild detergent, and over four weeks it left skin more hydrated, with most people happy with the hydration it gave.
Lactobacillus Ferment Lysate suits daily use and pairs naturally with hydrating ingredients like hyaluronic acid, since its own role is more about supporting skin's underlying balance than adding moisture directly.
Studied on skin, a cosmetic made with ferment lysates of a lactic acid bacterium helped skin hold on to its moisture after its barrier had been challenged with a mild detergent, and over four weeks it left skin more hydrated, with most people happy with the hydration it gave.
Lactobacillus Ferment Lysate suits daily use and pairs naturally with hydrating ingredients like hyaluronic acid, since its own role is more about supporting skin's underlying balance than adding moisture directly.
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Made from fermented lactic acid bacteria (not a live microorganism), used to help support skin's natural balance
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Helps skin hold on to moisture when its barrier is under stress
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Studied on skin for increased hydration
Questions
What is Lactobacillus ferment lysate?
It is a fermentation product made with lactic acid bacteria of the genus Lactobacillus, which is then lysed, meaning the cells are broken down. It is used in skincare to help keep skin in good condition. The name describes the process: ferment for the fermentation, lysate for the broken-down cells. (COSMILE Europe)
Is Lactobacillus Ferment Lysate the same as Lactobacillus Ferment?
No. They are two separate ingredients. Lactobacillus Ferment is the fermentation product itself, made by using lactic acid bacteria to ferment a starting material, usually a plant-based one. Lactobacillus Ferment Lysate goes one step further: the cells are broken down (lysed). Both help keep skin in good condition. (COSMILE Europe)
Is Lactobacillus ferment lysate a probiotic?
No. A lysate contains no living bacteria, because it is made by breaking the cells down, a process called lysis. That is why it is not a probiotic. (COSMILE Europe)
Is there research on ferment lysates in skincare?
Yes. On skin, a cosmetic containing ferment lysates of a lactic acid bacterium helped reduce moisture loss after the skin's barrier had been challenged with a mild detergent, and over four weeks it left skin more hydrated. (Lee et al., 2023)
Where it comes from
Lactobacillus is a genus of lactic acid bacteria. To make a ferment lysate, a culture is fermented and the resulting cells are then broken down (lysed), so the finished ingredient is a fermentation product rather than living bacteria. (COSMILE Europe)
The research
- Lee M, Kim MS, Jang SH, Kim H, Kim GS, Lee H, et al. Cera-Glow, ferment lysates of Lacticaseibacillus rhamnosus IDCC 3201, improves skin barrier function in clinical study. Journal of Cosmetic Dermatology. 2023;22(6):1879-1886. PMID: 36718839. (opens in a new tab)
- COSMILE Europe (Cosmetics Europe) cosmetic ingredient database: Lactobacillus Ferment Lysate (function: skin conditioning; origin: biotechnology) (opens in a new tab)
